Lions Mane

Our Premium Lions Mane supplement is standardized to 30% Polysaccharide extract.
Hericium Erinaceus is known in Asia as an important wellness fungus as well as a health-promoting food. * Hericium Erinaceus (also called Lion's Mane or Yamabushitake mushroom) is consumed as a food in Japan and China. It has attracted much research due to its health benefits as a home remedy for health ailments. Its fruiting bodies and fungal mycelia exhibit various health properties. *

The physiological systems in the body should be balanced in order to maintain whole-body homeostasis. Once the balance is disturbed, dis-ease can occur. There is increasing evidence to indicate that oxidative stress may affect a myriad of health challenges, including cancer and Alzheimer's. Reactive oxygen species (ROS) and lipid peroxides are damaging compounds involved in the oxidative stress process. A number of studies have demonstrated the close association between health and well-being and the intake of antioxidant-rich foods, including mushrooms [3]. As a wellness related mushroom, Lion's Mane has an abundance of active substances that may support ant-ioxidative roles to reduce ROS-associated health ailments. *

Fatigue can be defined as a situation in which the capacity for work is diminished and the efficiency of accomplishment is reduced, and it can be classified as physical or mental, depending on its cause. Liu et al., 2015 studied the energy supporting properties of polysaccharides extracted from Lion's Mane. This fungus has significant fatigue supporting properties that could be seen by a decrease of blood lactic acid, serum urea nitrogen, and malondialdehyde, as well as an increase in tissue glycogen content and antioxidant enzyme activity [4]. *

The worldwide prevalence of diabetes for all age groups was estimated to be 2.8% in 2000 and it is projected to reach 4.4% in 2030 [5]. The aqueous extract of Lion's Mane may possess hypoglycemic and hypolipidemic suportive properties [6]. Some studies suggest assistance in healthy insuIin levels when food is supplemented with Lion's Mane. Similarly, Hao et al., (2015) studied the protective effects of Lion's Mane on alcohol-induced hepatotoxicity. Lion's Mane supported serum alanine aminotransferase, aspartate aminotransferase, and maleic dialdehyde levels. This fungus had a significant role in supporting hepatic health in relation to alcohol [7] *

Lion's Mane has a significant cell-calming and cell-homeostasis in the management of replication and reproductive abilities effect on primary myeloma cells, human myeloma cell lines, and other cell lines in in vitro tests [8]. Another study discovered that Lion's Mane could provide gastrointestinal health support. Diling et al., (2017) demonstrated that Lion's Mane extract could promote the health of beneficial gut bacteria and support host immunity. The study provided potential clinical evidence on Lion's Mane in the management of bowel health by regulation of gut microbiota and the immune system [9]. The multipurpose biological properties of Lion's Mane have been reported in many brain health studies. Regular administration can may offer mood and anxious thought support by enhancing adult hippocampal neurogenesis [10]. *

Stroke is the 4th leading cause of death and the primary cause of long-term disability worldwide. Ischemic insult produces excessive free radicals, which then causes abnormal endoplasmic reticulum stress signaling that has been linked to apoptosis. These events then induce apoptotic cell death in neurons. A study by Kam-Fai Lee et al., (2014) confirmed the nerve-growth properties of Lion's Mane mycelium, which include the support of neuron health [11]. Another extraordinary study was conducted by Chang et al., (2016) on Lion's Mane and its antiangiogenic potential. The promising results discovered the factor responsible for angiogenesis, proving that Lion's Mane is a potential antiangiogenic supporting agent [12]. *

It has been proven that the dysregulation of nerve growth factor signaling is linked to early stages of neurological diseases. Erinacine A, (the main representative of compounds in Lion's Mane extract) has demonstrated epinephrine-stronger nerve growth factor-inducing activities in in vitro and in vivo tests [13]. In a recent study, it was discovered that a unique polysaccharide fraction from Lion's Mane mycelium designated EP-1 exhibited gastro-health supporting properties [14]. *

Lion's Mane contains proteins, unsaturated fatty acids, carbohydrates and a variety of trace elements, including phosphorus, sulfur, calcium, magnesium, zinc, iron and copper. All the nutrients serve important roles in the multiple physiological systems of humans, including the nervous, digestive, circulatory and immune systems. *

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