Saw Palmetto

Our Premium Saw Palmetto supplement is standardized to 45% Fatty Acids extract. Serenoa repens, commonly known as Saw Palmetto, is a small, low-growing, dwarf-palm tree, native to North America, particularly Florida.

The American-Indians used Samw Palmetto berries medicinally and as a food source. They were used traditionally for a wide range of health ailments, like lung health, common colds,urinary health, and as a bedroom support supplement. The Mayans drank it as a tonic, and the Seminoles used the berries as an expectorant and antiseptic. Since the 1990s, saw palmetto has been one of the top 10 top-selling herbal medicines in the United States [1]. Research suggests that the fatty acids in saw palmetto extracts are responsible for its health benefits. The fatty acid content of saw palmetto supplements has been found to be in percentages ranged from 40.7% to 80.7% [5]. *

The extract of saw palmetto is the herbal extract most frequently used to support a healthy urinary tract and prostate, and evidence from over 35 clinical trials supports the use of standardized saw palmetto extract for this. Use of Saw Palmetto has shown to support optimal peak flow, as well as night time toilet visits [2]. Plant extracts are also widely used for lower urinary tract health in the United States and Europe [3]. In 2007 U.S. survey, 17.7% of adults reported use of a natural product, and 5.1% of users had taken saw palmetto [4] *

A systematic literature review of 11 studies identified saw palmetto supplements as one of five commonly used complementary or alternative medicine modalities by men with prostate health issues (1.9%–24.9%) [6]. Saw palmetto extracts predominantly consist of medium-chain fatty acids (~90%) such as laurate and myristate responsible for its ability to inhibit 5α-reductase [7]. Many studies suggest saw palmetto fatty acids may support healthy cell production and the management of cell mutation. *

Research also suggests Saw Palmetto may support healthy live function, and optimal hair growth in men. *

Bacterial prostatitis is a common condition responsible for about 5-10% of all prostatitis cases. Chronic bacterial prostatitis classified as type II, are less common but is a condition that significantly hampers the quality of life, because not only is it a physical condition but also a psychological distress. Saw palmetto nutritional supplement show potential as a support for chronic bacterial prostatitis, in comparison with antibiotic treatment alone [9]. *

Human gliomas which originate from neural stromal cells are the most common and malignant brain tumor in humans. The glioma has a strong ability in promoting the formation of angiogenesis and microvascular network to provide the tumor with nutrients for the sake of further invasion and metastasis. So, the treatment of antiangiogenesis therapy has become an important method in glioma. It is found that saw palmetto extract is supportive for human glioma through STAT3 signal pathway. Saw palmetto extract may be useful as an adjunctive agent for individuals with glioma and other types in which STAT3 signaling is activated [10]. The results suggest that saw palmetto extract can increase the apoptosis of glioma cells. *

Liver cancer is one of the most prevalent human malignancies all over the world. As the sixth most common cancer, there are 782,000 new cases of liver cancer diagnosed annually and the death rate is increasing annually [11]. Saw Palmetto fatty acid-rich fraction exhibited significant cell mass support on human hepatocellular carcinoma [12]. Hepatocellular carcinoma (HCC) is the major form, accounting for 85% of liver cancer cases. The fraction is an adjuvant targeting cell mass neovascularization with no toxicity or any adverse side effects or weight loss. *

It is suggested that Saw Palmetto Extract has various health mechanisms (eg, inhibition of 5a-reductase, anti-androgenic effects, anti-proliferative effects, cell-calming effects, and anti-edema effects). However, most of these pharmacological effects were observed at relatively high concentrations or large doses of Saw Palmetto Extract. *

The extract contains 70-95% free fatty acids like capric, caproic, caprylic, lauric, myristic, oleic, linoleic, linolenic, stearic and palmitic acids with their ethyl esters and glycerides that occur most likely during the extraction process. Further phytosterols like l-sitosterol and l-sitosterol 3-O-D-glucoside, campesterol, and stigmasterol are found with about 0.1% of the total mass of the berries. Other constituents are alcohols, carbohydrates such as mannitol and polysaccharides with galactose and arabinose, triterpenes, aromatic acids like ferulic and vanillic acid, l-carotens, the vitamine E derivates l-tocopherol and l-tocopherols, mono-acyl glycerides like 1-monolaurin and 1-monomyristin, and the monoamine tyramine.

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